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Saudi Arabia’s Global Longevity Revolution

Witness how Estée Lauder's alliance with the Stanford Center on Longevity blurs the lines between aesthetic beauty and scientific research. Marvel at Saudi Arabia's Hevolution Foundation, channeling an unprecedented investment into the realm of healthspan research. Be intrigued by the role of dietary elements in altering the course of aging, as revealed in recent mice studies.  Each narrative in this issue unfolds a layer of the complex tapestry of aging, portraying a future where longevity is synonymous with enhanced quality of life, rooted in scientific ingenuity and global cooperation. Metformin, long known for its role in diabetes management, is now being reimagined as a key player in extending human lifespan. Rapamycin, a discovery from the soils of Easter Island, holds the intriguing potential to alter the course of aging at a cellular level. NAD, a cornerstone of cellular processes, presents a promising avenue in combatting age-related decline.
Silhouettes symbolizing longevity-related societal taboos
Challenging Longevity Taboos: Facing the Unspoken in Ageing.

Welcome to this week’s science and research edition of Longr Reads, where we navigate the ever-evolving landscape of longevity. Today, we embark on a journey through groundbreaking collaborations and scientific breakthroughs that are reshaping our understanding of aging. 

Witness how Estée Lauder’s alliance with the Stanford Center on Longevity blurs the lines between aesthetic beauty and scientific research. Marvel at Saudi Arabia’s Hevolution Foundation, channeling an unprecedented investment into the realm of healthspan research. Be intrigued by the role of dietary elements in altering the course of aging, as revealed in recent mice studies. 

Each narrative in this issue unfolds a layer of the complex tapestry of aging, portraying a future where longevity is synonymous with enhanced quality of life, rooted in scientific ingenuity and global cooperation.

Let’s learn more …


Estée Lauder and Stanford Center on Longevity (Cosmetics Business)

In an exemplary display of industry-academia synergy, Estée Lauder joins forces with the Stanford Center on Longevity, heralding a new era in beauty and age reversal. 

This ambitious venture, spanning three years, promises to fund research that challenges and refines our perceptions of aging and vitality. The collaboration will support post-doctoral fellowships and foster a deeper understanding of how skin, our largest organ, conveys vitality and wellness. 

This initiative dovetails with the launch of Estée Lauder’s Longevity Collective and their groundbreaking skin care innovation, Re-Nutriv Ultimate Diamond Transformative Brilliance Soft Crème, employing Sirtivity-LP technology for visible age reversal. 

By intertwining scientific rigor with skincare, Estée Lauder not only advances its legacy in pioneering longevity research but also reimagines skincare for future generations, a testament to their commitment to transcending conventional beauty paradigms.

Saudi Arabia’s Global Longevity Revolution (Arab News)

In a bold and visionary move, Saudi Arabia’s Hevolution Foundation is redefining the frontiers of healthspan research with its staggering $1 billion annual commitment. 

This initiative, integral to Saudi Vision 2030, is set to catalyze global efforts in understanding and extending healthy human life. Hevolution’s approach, blending academic and private sector development, aims to democratize strategies that enhance health longevity, effectively shifting the healthcare focus from treatment to prevention. 

The foundation’s collaboration with XPrize, announcing a $101 million prize for reversing aging aspects, underscores its innovative ethos. 

Such pioneering endeavors by Hevolution not only promise to extend healthy living years but also aim to alleviate the societal and financial burdens of age-associated illnesses, positioning Saudi Arabia at the forefront of the global longevity research movement.

One Amino Acid Increases Lifespan of Middle-Aged Mice Up to 33% (Science Alert)

In a riveting scientific discovery, researchers unveil the impactful role of dietary isoleucine restriction in prolonging the lifespan and healthspan of mice. 

This study illuminates the potential of manipulating dietary components to significantly influence aging and overall health. By reducing isoleucine intake, the study observed remarkable improvements in lifespan, health measures, and metabolic health in mice, challenging existing notions about diet and aging. Intriguingly, despite an increased caloric intake, mice on a low-isoleucine diet maintained leaner body weights, suggesting a profound metabolic shift. This research opens doors to potential human applications, hinting at dietary or pharmaceutical interventions to combat aging. 

As we advance in understanding the complex interactions between diet and aging, such studies pave the way for innovative approaches to enhance longevity and quality of life in humans.


As we conclude this week’s edition of Longr Reads, we’ve explored a diverse array of innovative strides in the world of longevity. 

Estée Lauder’s collaborative venture with Stanford Center on Longevity marks a significant leap in integrating scientific research into the realm of beauty and skincare, challenging and reshaping our perceptions of aging. The Hevolution Foundation, with its ambitious vision and substantial financial backing, is redefining the scope of healthspan research, advancing Saudi Arabia’s prominence in global healthcare innovation. Furthermore, the enlightening study on dietary isoleucine restriction in mice opens new avenues in nutritional science, indicating profound implications for human aging and healthspan.

 Together, these developments paint a future where the journey of aging is embraced with intelligence, grace, and proactive innovation, heralding an era where the quality and vitality of life are paramount.

Until next time,

The Longr Reads Team


“Somewhere, something incredible is waiting to be known.”

Carl Sagan, Astronomer


Longr Reads’ of the Week

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  • ‘Long-lost best friends’: the longevity movement finds psychedelics (The Guardian)
  • From Longevity To Aging In Place, These Are The Top Areas For Senior-Focused Startups (Crunchbase)
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